Pioneering the Path: Early Prediction of Neurodivergent and Genetic Diseases through Predictive Analytics

Kasturi Goswami
4 min readJul 31, 2023

Much like the intricate diverse mosaic nature of humans, the world of ailments is increasingly becoming more complex. However, the almost equal-spaced rate of evolution of the treatment landscape has been a boon. Corona Virus had much to say regarding the life-saving vaccine study, production, and distribution. Ailments adapt, and so does the field of healthcare.

Challenging Conventional Care

Neurodivergent and genetic disorders are part of a spectrum of healthcare study and delivery that resonates with the very troubled and complex system of the brain or the very being of the human body, the DNA. These conditions challenge conventional diagnostic approaches, necessitating innovative solutions to ensure timely interventions.

Mrs. Walter or Lisa Baker

People loved Mrs. Walter — The friendly new neighbor. But she was much more than the homemaker who brought in the occasional cookies. With a master’s in literature and a job as a community college academician, Lisa Baker was a fiercely independent young woman once. She had learned to survive from an early age, having seen her mother die due to tuberculosis and her father slowly rot away due to dementia.

By the late-90s, she met the most respectable young man driven by a passion for sales. Wedding bells chimed, and within two years of their marriage, Lisa Baker completely transformed into Mrs. Walter. Being a mother is the greatest happiness, they say. So Lisa adjusted (quit her job) and settled down.

Mr. Walter’s job demanded frequent travel. Thus, travel sickness was part of life. And even though patience is a virtue, retirement was a faraway dream. The stress was unnerving for Mrs. Walter. She made a rented house home every two years.

By the time she was in her mid-40s, what would rather be happy weekends turned into frequent visits to the St. Mary’s hospital. Lisa was taken in by dementia. The doctors said the stress of constant moving and the sheer loneliness of being home-bound had triggered her condition, called in the devil much earlier than intended, as dementia ran in her family genes.

If only people knew what she was going through. If only she sought out help for her depression.

Taking a Stand With Value-Based Care

Predictive analytics emerges as a guiding light within the unfolding narrative, offering the promise of early detection and personalized care.

The goal of early prediction is not simply to anticipate disorders but to intervene early enough to prevent their full expression.

Healthcare Providers

Predictive analytics, driven by artificial intelligence (AI), offers a powerful tool to help care providers achieve their vision. Predictive models can be created by integrating vast datasets, including genomics, electronic health records (EHRs), and real-time patient monitoring.

These machine-learning (ML) models have the potential to forecast disease trajectories and possible interventions, empowering physicians to initiate targeted initiatives before irreversible damage occurs.


U.S. policymakers are championing interoperability and secure data exchange to harness the power of AI and data-driven technologies.

By breaking down silos that hinder the flow of critical patient information, policymakers are fostering an environment where predictive analytics can leverage comprehensive datasets, encompassing genetic data, clinical records, lifestyle factors, and social determinants of health, ensuring timely interventions and precise risk assessments.

Spearheading Value-Based Care

Value-Based Care prioritizes the delivery of quality care over every other aspect related to the quantity of care meted out. The maintenance of care delivery is the most critical agenda of U.S. healthcare. Thus, curbing a situation before its full-on surfacing with the help of predictive models to initiate timely and personalized responses is an excellent way to manage the quality of care.

The U.S. government funds research and development (R&D) facilities to build robust data repositories that serve as a foundation for predictive models. The Centers for Medicare & Medicaid Services (CMS), in turn, incentivizes care providers to adopt these predictive care delivery approaches.

This proactive outlook improves patient outcomes and reduces healthcare costs by preventing complications and hospitalizations.

Initiatives such as the Precision Medicine Initiative (PMI) and the All of Us Research Program are instrumental in pushing the boundaries of early prediction and personalized medicine.

Roadblocks to Data-Driven Innovation

The journey toward predictive analytics is not without its challenges. Collaborative efforts among stakeholders are paramount to addressing these challenges. Ethical considerations loom large, necessitating robust frameworks for data privacy and consent. While data sharing is essential, patient information must be protected.

Despite the significant advancements in AI to help predict care emergencies and likewise address roadblocks to data-driven initiatives, the questions still arise-

Can the healthcare industry possibly foster a culture of data-driven innovation successfully, one that permeates every aspect of patient care?

How can care providers and policymakers ensure equitable access to predictive analytics, ensuring its benefits extend to all segments of society?

Looking Ahead

In the grand tapestry of U.S. healthcare growth, predictive analytics intertwines with medical expertise to empower patients and physicians, illuminating the path toward personalized care and improved outcomes.

Armed with data-driven insights and empathetic care, healthcare providers become architects of proactive interventions, shaping brighter futures for those navigating the complexities of rare and inherited conditions.



Kasturi Goswami

I head the content team of a digital transformation startup. Medium is an outlet for my itch to write something that isn't part of my job.